Senior Associate, Translational Proteomics

Location: Roivant Discovery 451 D Street, Boston, MA 02210 USA

At Roivant, we are passionate about discovering and developing new drugs to impact patients' lives. Since its inception in 2014, Roivant has launched over 20 portfolio companies (Vants), overseen 5 successful IPOs, established a $3B partnership with a global pharma, built a pipeline of over 40 assets across various modalities and therapeutic areas, and delivered 8 successful phase 3 readouts. Roivant is currently building new capabilities in drug discovery and expanding its existing development engine to become the world's leading tech-enabled pharmaceutical company. We believe that the future of drug discovery lies in integrating predictive and experimental sciences, to accelerate the path to new medicines. This role is an opportunity to be an architect of this paradigm shift and generate transformative benefit for patients

Position Summary:

The Translational Proteomics group within Translational Chemical Biology is recruiting a Senior Research Associate to the team. We are applying mass-spectrometry-based proteomics to expand the druggable proteome, deconvolute the mechanism of action of drugs, and prosecute difficult targets. The group is working closely with cross functional teams in chemistry, biology and data science to achieve these goals. This is an exceptional opportunity to join a newly founded group that is pushing the boundaries of mass spectrometry-based chemo-proteomics to accelerate the translation of basic science into clinical solutions.

The successful candidate will have a background in basic molecular biology/biochemistry techniques and ideally have a track record of accomplishments in academia or in the life sciences/pharmaceutical/biotechnology industry. Our group is committed to the professional and scientific growth of our team members. As a result, s/he must have a strong desire to learn. The successful candidate will have the opportunity to acquire novel analytical and scientific skills and will be exposed to cross-functional and collaborative drug discovery in a biotechnology environment.

Responsibilities:

  • Maintain cells in culture and perform drug perturbation experiments
  • Prepare samples for proteomic analysis (e.g., cell culture, tissue, body fluids)
  • Execute standardized biological/biochemistry assays (e.g., BCA, Bradford, Western blot, etc.)
  • Support automation of proteomic workflows
  • Maintain and calibrate mass spectrometry equipment, liquid handling robots and HPLCs
  • Schedule preventative maintenance services and repairs of equipment, order and keep stock of spare parts
  • Prepare laboratory reagents and perform HPLC purification/fractionation of complex peptide mixtures
  • Compile/analyze experimental data and maintain clear and accurate records of experimental work
  • Work closely with members of the proteomics team to coordinate, execute, and present experimental work

Requirements:

  • B.Sc. or M.Sc. degree in biochemistry, organic, analytical chemistry or related discipline
  • 3+ years of experience in a laboratory environment (biotech start-up experience preferred)
  • Previous experience in proteomics sample preparation and bioanalytical techniques (i.e pull-downs, enzymatic, BCA/Bradford assays, protein interaction assays) would be favorable but is not a must
  • Previous experience with complex laboratory equipment is a plus (e.g., MS or HPLC)
  • Team player with close attention to detail and strong time management skills
  • Strong written and oral communication
Apply